Kanemi Company in Kyusyu produced rice bran oil “Kanemi Rice Oil” and sold it in a market. This rice oil spread throughout western Japan, and was consumed in many households as good for health and beauty.
In February 1968, PCBs (polychlorinated biphenyls), used as a deodorant, were mixed in the rice oil in the process of production. PCBs with heat produced PCDFs(poly-chloro-dibenzofurans), a kind of dioxins, in them and the chemicals and Co-PCBs were mixed into the oil altogether.
Many people used that rice oil in cooking and got contaminated with dioxins and dioxin-like compounds.
Around March the same year, there were increasing number of people with health problems of unknown causes, such as skin eruptions, mattery swellings, numbness in limbs, skin pigmentation, a large amount of eye discharge, liver dysfunction, etc.
Word had it that the possible cause might have been "Kanemi Rice Oil", but in spite of all those symptoms, some people still believed that the oil was good for their health and kept using it until the analysis was finally conducted.
It was October the same year when this incident was reported in the newspaper. This stimulated further research and they found out that it had been caused by the polluted oil with PCBs. (Later, it turned out to be the combined pollution by PCDFs―byproducts of heated PCBs, and Co-PCBs. And the number of people who reported their illness at that time added up to 14,000.)
The fact is that, a little before the outbreak of the disease, a lot of chickens had been dead of unknown causes in western Japan.
At first, they were thought to be killed by an infectious disease, but later, the field survey found that "Dark Oil" in their feed was suspected, which is a byproduct of Rice Bran oil, and the rice bran oil used then was produced by Kanemi Company. But they failed to identify the exact cause of the incident, and as of June that year, it was concluded that the chickens had been killed by food pollution "most probably caused by deteriorated oil itself." The shipments of Dark oil were suspended in March of that year. As for Rice oil, however, they didn't conduct a further survey nor stop selling it, despite the fact that it was sold for human use.
If they had conducted a detailed survey of the Rice Oil ―
and if they had started searching for a cause of patients with peculiar symptoms ―
then the number of Yusho victims would have been much smaller.