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  • Japan
  • Story A high-school boy who has run away to Tokyo befriends a girl who appears to be able to manipulate the weather
  • runtime 1hour, 52 minute
  • directed by Makoto Shinkai
  • Actors Sei Hiraizumi
  • release Date 2019
Child of prague good weather. 2:28 Im obsessed with this part. Zhi Zi (Gardenia Fruit, Fructus Gardeniae, ?子) 100 g Extract granules, equal to g ( lb) dried raw herb. Best before date: was save: Select Format Pian (Tablets) Wan (Pills) Qty What does it do? In the term of Traditional Chinese Medicine (TCM), Property Zhi Zi is bitter, cold. Channels Zhi Zi influences Heart, Lung, San Jiao. Action Purges fire and removes irritability. Clears heat and promotes urination. Cools the blood and resolves toxicity. 作用 ?火除?,清?利尿,凉血解毒 How to use it Take 1 g each time, 1 time per day, or as instructed by a herbal practitioner. Dissolve in hot water or mix into yogurt. A measuring gram spoon is included with every bottle. ActiveHerb NEW Single Herb Extract Advantage Precaution Use single Chinese herbs or herbal extracts with caution. Professional advice is suggested. In TCM, Chinese herbs are mostly combined in the context of formulas to enhance each other's desirable action and to minimize any potential side effect. You may want to search our extensive collection of patent Chinese medicine to find the formulas that utilize the herb of interest. Side Effects Warning Allergy Info In the Media Reviews Gardenia Fruit (Zhi Zi) is rated 5. 0 out of 5 by 1. Rated 5 out of 5 by from Fast acting for decrease anxiety and anti inflammatory effects. Date published: 2016-07-01 Related Products Customers who bought this item also bought ?.
Child of weather full movie. Is not as brilliant and amazing as your name very strong love chemistry and brilliant storyline and not feel crying tear as Taki and Mitsuha finding each going through different time, tunnel, train and long staircase, and finally final moment meet each by asking their name. However, Weathering still deliver excellent visual anime, art style and combination of 3D and 2D merge together and can see a lot of effort because is very difficult and take a lot of time for produce or drawing 2D image scene by scene. Great main theme sound capture certain important scene, harsh working environment, charm and nice chemistry between Hina and Hodaka, feel touching moment and a bit realistic human culture, law, behavior and metropolitan of japanese people and some heroine supporting character and extra points for cameo. If is a solid excellent anime movie. Hope Shinkai produce next beautiful anime movie as always.
Chinese Medicine volume 13, Article?number: 65 ( 2018) Cite this article 2603 Accesses 3 Citations 1 Altmetric Metrics details Abstract Systems biology is an academic field that attempts to integrate different levels of information to understand how biological systems function. It is the study of the composition of all components of a biological system and their interactions under specific conditions. The core of systems biology is holistic and systematic research, which is different from the manner of thinking and research of all other branches of biology to date. Chinese herbal formulae (CHF) are the main form of Chinese medicine and are composed of single Chinese herbal medicines (CHMs) with pharmacological and pharmacodynamic compatibility. When single CHMs are combined into CHF, the result is different from the original effect of a single drug and can be better adapted to more diseases with complex symptoms. CHF represent a complex system with multiple components, targets and effects. Therefore, the use of systems biology is conducive to revealing the complex characteristics of CHF. With the rapid development of omics technologies, systems biology has been widely and increasingly applied to the study of the basis of the pharmacological substances, action targets and mechanisms of CHF. To meet the challenges of multiomics synthesis-intensive studies and system dynamics research in CHF, this paper reviews the common techniques of genomics, transcriptomics, proteomics, metabolomics, and metagenomics and their applications in research on CHF. Introduction Chinese herbal formulae (CHF) are the main forms of prescription for the clinical application of Chinese medicine (CM) and embody the holistic philosophy of CM and the characteristics of treatment according to syndrome differentiation. The complexity of the chemical compositions and the diversity of the prescription compatibility and therapeutic functions of CHF have long presented great difficulties in the research of CM [ 1]. In contrast to the single compounds of Western medicine, which have specific targets and definite modes of action, CHF contain many types of components. The effects of these chemical components not only are superimposed but also interact with each other through multiple targets, pathways and mechanisms [ 2, 3]. Slow progress in the research on the pharmacological mechanisms of CHF has hindered their application and popularization throughout the world, thus becoming one of the key scientific problems to be solved in the modernization of CM. Systems biology studies the interactions among different parts of a biological system at the cellular, tissue, organ and biological levels, and it quantitatively describes and predicts biological functions, phenotypes and behaviors through bioinformatics and through the computational and mathematical modeling of complex biological systems [ 4, 5]. Systems biology is an interdisciplinary field of study that focuses on complex interactions within biological systems, using a holistic approach instead of the more traditional reductionism of biological research. Systems biology is characterized by holistic and systematic research and explores the laws of life “from surface to point”, corresponding to the holistic view of CM. The process of applying systems biology for CHF research is summarized and illustrated in Fig. 1. Fig.?1 Overview of the applications of systems biology in CHF research With the development of high-throughput technologies and data analysis methods, such as genomics, proteomics, metabolomics and transcriptomics, an increasing number of studies have focused on clarifying complex biological phenomena at the systems level [ 6, 7]. Large amounts of information from omics technologies and computational studies, including bioinformatics, data mining and machine learning, have been used to understand biological phenomena to predict interactions of biological systems [ 8, 9]. As a complement to the traditional research mode, a novel CM pharmacological approach through the combination of network pharmacology, omics technologies and computational studies has been established to update the research paradigm from the current “one target, one drug” mode to a new “network target, multicomponents” mode [ 10]. The approach can discover the combinatorial rules and network regulation effects of CHF from a systems perspective and at the molecular level by prioritizing disease-associated genes, predicting the target profiles and pharmacological actions of herbal compounds, revealing drug-gene-disease comodule associations, screening synergistic multicompounds from CHF in a high-throughput manner [ 11], analyzing data through computational studies [ 12], and then clarifying the combinatorial rules and network regulation effects of CHF. Therefore, this article focuses on an overview of systems biology technology and the application of systems biology in CHF studies. Application of genomics in CHF research Genomics is an interdisciplinary field of science focusing on genome mapping, nucleotide sequencing and gene function analysis [ 13]. According to the time of development and research purposes, genomics is divided into the four branches of structural genomics, functional genomics, comparative genomics and pharmacogenomics. Common techniques in genomics Commonly used research methods in genomics include DNA sequencing and bioarray technology. According to different sequencing objects, DNA sequencing technology can be divided into the following categories. (1) Genome-wide association study (GWAS) typically focuses on associations between single-nucleotide polymorphisms (SNPs) or copy-number variations (CNVs) and traits [ 14]. (2) Exome sequencing uses sequence capture technology to capture and enrich genome-wide exon-region DNA for high-throughput sequencing [ 15], which can be used to find pathogenic and susceptible genes of complex diseases. (3) Methylated DNA immunoprecipitation sequencing (MeDIP-Seq) can quickly and effectively find the methylation regions in the genome, thus enabling a comparison of the differences in DNA methylation modification patterns between samples [ 16]. (4) Chromatin immunoprecipitation (ChIP) is used to investigate the interaction between proteins and DNA within cells and to determine the specific location in the genome with which various histone modifications are associated, indicating the targets of histone modifiers [ 17]. Genomics involves chip technology, including the single-nucleotide polymorphism array (SNP-A), array-based comparative genomic hybridization chip (aCGH), and methylated DNA immunoprecipitation chip (MeDIP-Chip). In addition to high-throughput sequencing and microarray chip technology, low-throughput technology, such as real-time fluorescence quantitative polymerase chain reaction (RT-PCR) and the TaqMan probe, are also needed for verification of genomics research. Application Genomics technology has the characteristics of being high-throughput, multifactorial, rapid and sensitive [ 18], and it can be used to systematically study the multicomponent, multipathway and multitarget effects of CHF systematically. Current studies have reported that genomics is used to evaluate the efficacy of CHF and to reveal the mechanism of action of CHF at multiple levels. Wen et al. [ 19] used microarray technology to compare the differences in gene expression between the Siwu decoction and estradiol in the human breast cancer cell line MCF-7, using a microarray and a connectivity map to evaluate the efficacy of the Siwu decoction and explore its molecular mechanism of action. The authors found that the Nrf2-mediated oxidative stress pathway might explain the mechanism of Siwu decoction’s cancer defense by using IPA software, and RT-PCR confirmed the overexpression of five genes in this pathway. This study demonstrates the feasibility of microarray technology in combination with other techniques for the evaluation of therapeutic efficiencies and mechanism studies of CHF. Wang et al. [ 20] reported the mechanism of the Danqi pill (DQP) in myocardial ischemia treatment by measuring gene microarrays in a rat model. After evaluating the effects of signaling pathways and metabolism, the authors found that DQP can reverse energy metabolic disorders to recover cardiac function. In addition, genomics has been used to analyze therapeutic targets of CHF and to predict other potential drugs. Tang et al. [ 21] examined therapy using Sini decoction (SND) on kidney yang deficiency in a rat model. Using an mRNA microarray with enrichment analysis, Wang et al. found that SND treatment can improve hypothalamic?pituitary?adrenal axis hormones. Kim et al. [ 22] connected GWAS diseases to CM by analyzing microarray gene expression and constructing disease-gene networks. The authors analyzed 14, 713 GWAS disease-CM-target gene pairs to propose potential drugs from CM. Considering that molecular docking technology may lead to omitted or incorrect information, Zhang et al. [ 23] proposed the GEPSI method to identify the target proteins of CM by calculating the similarities of gene expression. These reports are promising for the application of DNA microarray technology in the research of CM. However, other high-throughput technologies such as exome sequencing, MeDIP-Seq, ChIP, aCGH and SNP-A have not been used extensively to date in the study of CHF and, hence, need further research. It is expected that genomics or genomics combined with other omics analyses will offer comparatively high practical value with a systematic flow in the study of CHF. Application of transcriptomics in CHF research Transcriptomics technologies are techniques used to study gene transcription and transcriptional regulation. Unlike the static genome, the transcriptome is regulated by both exogenous and endogenous factors. Therefore, the transcriptome is a dynamic link between the genome of a species and its externa
Im someone whos skeptical of romances in movies, TV, etc. to the point of being cynical. But this moment got me. The visuals, the music, and that line of “I want you more than any blue sky!” hit home. What a beautiful moment from a magnificent movie. The child of the weather movie. Remember him,when i listen to this song.??.

I want to pay it back and spend it all on you

Ini Film Hampir Bikin Gw Nangis. Cerita Hodaka Dan Hina Memang Indah,Film Nya Juga Indah, Memang Ini Film Yang Direkomendasi. Link blog nya dong please penasaran aku ini?. But still, I need to know. My Lucky Star My Lucky Star promotional poster by SETTV Also known as 放羊的星星 fāng yáng de xīngxīng Genre Romance, Comedy Created by Chen Yushan (?玉珊) Written by Du Xinyi (杜欣怡) Directed by Chen Mingzhang Starring Jimmy Lin Yoo Ha-na Leon Jay Williams Opening theme "極速愛情" Jisu Aiqing by Shivia Lee Ending theme "對望" Dui Wang by Jimmy Lin Country of origin Republic of China (Taiwan) Original language(s) Mandarin No. of episodes 20 Production Executive producer(s) Fang Xiaoren, Hu Hanxin, Chen Yushan Running time 90 mins (Sundays from 21:30 to 23:15) Production company(s) Sanlih E-Television Release Original network Taiwan Television (TTV) Original release 11 March ? 22 July 2007 Chronology Preceded by Engagement For Love (愛情經紀約) Followed by Ying Ye 3 Jia 1 External links My Lucky Star TTV homepage My Lucky Star ( Chinese: 放羊的星星; pinyin: fàng yáng de xīngxīng; literally: 'the stars who tend the sheep') is a 2007 drama starring Jimmy Lin, Leon Jay Williams, and Yoo Ha-na. It was produced by Sanlih E-Television and directed by Chen Ming Zhang (陳銘章). [1] The series was first broadcast in Taiwan on free-to-air Taiwan Television (TTV) from 11 March 2007 to 22 July 2007, every Sunday from 21:30 to 23:15 and cable TV Sanlih E-Television (SETTV) on 17 March 2007 to 28 July 2007, every Saturday at 21:00. The premiere episode on TTV achieved an average rating of 2. 24 and peaked at 2. 4. [2] Synopsis [ edit] In the beginning, Xia Zhixing (Ah Xing) was a jewelry con artist, posing as various jewellery company representatives to trick customers into purchasing fake goods. Just like the boy who cried wolf, she had told one too many lies. As a result of this, she is caught for covering up for Shisan Ge (the man she ran off and started jewellery conning with many years ago) and is put in jail for a year. But when she crosses paths with Zhong Tianqi, a rebellious young master of a jewellery empire who is on the run having stolen an important jewel called the "Queen Mary" from his father's company, E-shine, the pair gradually become more and more involved with each other, though reluctantly at first. Ah Xing is drawn to him because, unlikely as it is, he seems to be the only one who believes in her. Eventually, several events after they first meet, they fall in love. However, because Tianqi is from a wealthy background and Ah Xing is not, his father will not let them see each other, provoking Tianqi to leave with Ah Xing in anger and demands he no longer wants to be part of the family company. He inspires Ah Xing to become a jewellery designer after seeing some of the forged copies she has produced, though Tianqi's father does everything he can to separate his son from the girl he sees as nothing but shameful. Ou Yaruo ? a worker at the company who previously had a relationship with Tianqi but then betrayed him by trying to marry his brother, Tianjun, because he was the first young master of Eshine ? is also hateful towards Ah Xing as she still has feelings for Tianqi. Tianjun, however, is in love with Ou Yaruo but knows she does not love him back. Tianqi is a passionate and skilled racer and helps to save the residents of Tomorrow Town (Ah Xing's hometown) from the gang led by Fa Ge, where he is seen as a local hero afterward. After Tianqi is brutally beaten up when they aim to seek revenge on him, Ah Xing agrees on Tianqi's father's orders not to see Tianqi anymore when she sees how much pain he has had to suffer because of her. Tianqi is told he cannot race in the future due to a broken hand. Once Tianqi has recovered, Ah Xing throws away the blue sapphire earring Tianqi presented to her when they first fell in love to convince him that her feelings now are real. Tianqi searches through the rain for the earring but cannot find it and is then led away by Ou Yaruo when he starts to become agitated. Ah Xing has a change of heart and tries to tell Tianqi she's sorry but the car is already driving away. [ citation needed] Tianqi learns his father is suffering from Parkinson's disease and tries for his family's sake to forget about Ah Xing. But he still has strong feelings for her no matter how hard he tries, so does not and cannot give up on their love. In the end she agrees to meet him at the cable cars in Tomorrow Town as she, too, cannot hide the way she feels. Tianjun drives Ah Xing to meet Tianqi, not realising that Ou Yaruo has tampered with the car as she thought her father would be driving it. The car crashes, killing Tianjun and leaving Ah Xing crawling on her knees to find help. Meanwhile, Tianqi waits for Ah Xing to arrive, which she never does. He finds out about his brother's death and from then on blames Ah Xing for leaving Tianjun to die and breaking his heart. He vows he will never forgive her and will hate her forever. 5 years later, Zhong Tianqi is a changed man. He is now the ruthless young boss of Eshine, and has become very cold and bitter since his brother and father's deaths. Ah Xing is living with her uncle, Guang Ming, and is the guardian of Shisan Ge's 5-year-old daughter, Nini, because he is in prison and cannot look after her. Nini is eager for Ah Xing to accompany her to meet the famous superstar Han Zhiyin who just so happens to have signed a contract with Eshine. Ah Xing agrees to go and as a result ends up winning the chance to spend 8 hours handcuffed to Han Zhiyin. This leads to Ah Xing and Tianqi becoming reunited after several long years during which he publicly reveals his hate about her and what type of person he has been led to believe she is. He still believes she was the one who killed his brother and vows to find out the truth. However, his old feelings are rekindled and he finds himself falling for her all over again, after the pair are involved in several events together. During this, Han Zhiyin discovers that Tianqi is his older half-brother because of a secret romance between Tianqi's father and Han Zhiyin's mother many years ago. Han Zhiyin feels resentment and jealousy towards Tianqi because Tianqi had been brought up well by their father (who abandoned Han Zhiyin and his mother and wanted nothing to do with them), whereas Han Zhiyin lived most of his life on the streets before becoming a celebrity. The two newly discovered brothers fight for Ah Xing's love for a while, but Ah Xing tells Han Zhiyin that what he feels for her isn't real and that he is just trying to take what Tianqi has for his own. Tianqi and Ah Xing have a fight about the contract they signed, but it was a misunderstanding. Tianqi was trying to make a new contract with Ah Xing which she could never break. That was to marry Tianqi. Tianqi also learns the truth about that fateful day in which Tianjun died but does not blame Ou Yaruo for it. As they stand by Tianjun's grave, Ou Yaruo allows herself to be escorted away by the police because she says that with Tianjun by her side, she is not afraid. She puts on the wedding ring that Tianjun presented to her before his death and recalls the memory of his proposal. The drama ends 2 months later where Han Zhiyin is running Eshine and Ah Xing is revealed to be pregnant with Tianqi's child. Han Zhiyin refuses to give Tianqi a 10-month break so easily. He challenges Tianqi to one last car race to determine who will run the company for the next 5 years. [ citation needed] Cast [ edit] Jimmy Lin as Zhong Tianqi ( 仲天騏) Yoo Ha-na as Xia Zhixing ( 夏之星) Hong Xiaoling as Ou Yaruo ( 歐雅若) Leon Jay Williams as Zhong Tianjun ( 仲天駿) Lee Wei as Han Zhiyin ( 韓志胤) Wang Dao as Zhong Wei ( 仲威) Dong Zhicheng as Guang Ming ( 光明) Huang Yurong as Zhao Shisan ( 趙十三) Chen Weimin ( 陳為民) as Fa Ge ( 發哥) Zheng Xiaohui ( 鄭曉慧) as He Baozhu ( 何寶珠) Tsai Pei-lin as Jin Shanmei ( 金善美) Guo Shi Lun as Wu Renyao ( ?仁耀) Niu Chengze Meng Tingli ( 孟庭麗) Song Zhiai as Ming Mei ( 明美) (ep. 01) Fu Peici ( 傅佩慈) as Nini ( 妮妮) Li Zhiqin ( 李之勤) as Zhong Hua ( 仲華) Cheng Boren ( 程伯仁) as George Lin Yihong as Jason Renzo Liu as Hedda Soundtrack [ edit] My Lucky Star Soundtrack album by Jimmy Lin, Shivia Li, James He Released 11 August 2008 Genre Mandopop Language Mandarin Label Decca Records (TW) My Lucky Star Original TV Soundtrack (放羊的星星 電視原聲帶) was released on 11 August 2008 by Jimmy Lin, Shivia Li and James He under Decca Records (TW). It contains eighteen songs, in which eleven songs are various instrumental versions of the seven original songs. The opening theme song is "Ji Su Ai Qing" or "Extreme Speed of Love" by Shivia Lee, while the ending theme song is by Jimmy Lin entitled "Dui Wang" or "Looking At Each Other". [3] Track listing [ edit] No. Title Singer(s) Length 1. "Looking At Each Other Korean ver. " (Dui Wang) Bii 2. "Extreme Speed of Love" (極速愛情 (Ji Su Ai Qing)) Shivia Li 3. "Looking At Each Other" (對望 (Dui Wang)) Jimmy Lin 4. "Paradise" Shivia Li 5. "Our Commemoration" (我們的紀念 (Wo Men De Ji Nian)) Shivia Li 6. "Goodbye My Love" He Jun Ming 7. "Be Brave Breaking Up" (堅強分手 (Jian Qiang Fen Shou)) He Jun Ming 8. "Magnificent Sadness inst. " (Hua Li De Bei Shang) 9. "Keep Me Company in Jail Cell #107 inst. " (Pei Wo Zai 107 Hao Lao Fang) 10. "Whirlpool in the corner of the Eye inst. " (Yan Jiao De Xuan Wo) 11. "Keep the Commemoration inst. " (Liu Zhu Ji Nian) 12. "First Time Goodbye inst. " (Goodbye Chu Ti Yan) 13. "Stars in Heaven inst. " (Tian Tang Shang De Xing Xing) 14. "White Window Screen inst. " (Bai Sha Chuang) 15. "Slow Heated Notes inst. " (Man Re Bi Ji) 16. "Love Paradise inst. " (Lian Ai Paradise) 17. "Underground Racing inst. " (An Biao) 18. "Holy War Lucifer inst. " (Sheng Zhan Lu Xi Fa) International Broadcast [ edit] Philippines - Q-11 dubbed in Tagal
I was also shocked when he and she appeared. Child of weather anime. The animation is BREATHTAKING. They really put a lot of time into this. Looks really good. How does this man make amazing and well written videos like this in like two days? You are a great dude Digi. Child of prague and weather. Child of water. Taki has a more dialouge than mitsuha it's very very sad. I wanna see them together in a scene though... but it did not. This movie was so beautiful and the pure greatness of this movie cant be put into words damn u shinkai. Child of weather report.
5:05 Jojo ! even Kimi No Nawa isn't safe from Jojo reference. Anyone else watching Weathering With You tonight. Your Name: Finding love in destiny Weathering with You: Changing destiny for love. The child of weather.
Child fear of weather.

Child's definition of weather

なんかもう 「米津玄師」っていうワードが神々しく見える. Child of water & little blue rock. Child of. I think the story structure was somewhat similar, the themes felt very different. Child of weather. Child of weather channel. I need to know, is there still anything that love can do. Child of weather makoto shinkai. Child scared of weather. I just want to know one thing that When they finally meet each other, after telling their name each other, Will they remember all those memories happened back in past. Child of water and little blue rock. It's good that we can Hear every song of weathering with you and your name.??. ???? ??? ??? ??? ???? ??? ????... ????? ???? ????. Makoto Shinnkai: The only one who can beat me is me. 夏は暑いから外に出るの嫌っていう理由で海獣の子供を映画館に見に行かなかった自分なんなん.腹立つ. VERY NICE SONG. First trailer song.


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